Native Bovine UBB Protein, Tag Free
Product Description
Cat
IMP-6662
Official Symbol
UBB
Product Overview
Native bovine Ubiquitin purified from erythrocytes.
Description
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.
Expression System
Rrythrocytes
Species
Bovine
Tag
Tag free
Form
Presentation State: Purified
State: Lyophilized purified protein
Purity
> 90% by SDS-PAGE.
Applications
ELISA
Storage
Prior to reconstitution store at 2-8 centigrade. Following reconstitution store the protein undiluted at -20 centigrade. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Reconstitution
With sterile DI water.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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