Recombinant Cavia porcellus Ctla4 protein, C-His Tag
Product Description
Cat
IMP-551
Official Symbol
Ctla4
Product Overview
Recombinant Cavia porcellus CTLA4(XP_003474228.1)(Ala37-Asp161)  is expressed in Yeast, fused with a 6His tag at the C-terminus.
Description
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Expression System
Yeast
Species
Cavia porcellus
Tag
C-His Tag
Form
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Molecular Mass
18-40kDa, reducing conditions.
Protein length
Ala37-Asp161
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Purity
Greater than 90% as determined by reducing SDS-PAGE.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Concentration
Please refer to product label for detailed information.
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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