Recombinant Cotton Rat CD8A Protein (Ser24-Asp182), C-6×His-tagged

Product Description

Cat

IMP-10292

Official Symbol

Cd8a

Product Overview

Recombinant Cotton Rat CD8 alpha protein (Ser24-Asp182) with a C-terninal 6×His tag was expressed in Mouse myeloma cell line.

Description

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.

Expression System

Mouse myeloma cell line

Species

Cotton Rat

Tag

C-6×His

Predicted N Terminal

Ser24

Form

Lyophilized from a 0.2 μm filtered solution in PBS.

Molecular Mass

Predicted Molecular Mass: 18 kDa
SDS-PAGE: 26-32 kDa, reducing conditions

Protein length

Ser24-Asp182

Bio-activity

Bioassay data are not available.

Endotoxin

<0.10 EU/μg of the protein by the LAL method.

Purity

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Reconstitution

Reconstitute at 250 μg/mL in PBS.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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