Recombinant Cynomolgus C3 Protein, C-His-tagged
Product Description
Cat
IMP-1376
Official Symbol
C3
Product Overview
Recombinant cynomolgus complement C3 (XP_005587776.1) (Met1-Asn1663) was expressed with a polyhistidine tag at the C-terminus.
Description
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Expression System
HEK293
Species
Cynomolgus
Tag
C-His
Predicted N Terminal
Thr23
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.
Molecular Mass
The recombinant cynomolgus complement C3 consists of 1652 amino acids and predicts a molecular mass of 186.40 kDa.
Protein length
Met1-Asn1663
Endotoxin
< 1.0 EU/μg protein as determined by the LAL method.
Purity
> 90 % as determined by SDS-PAGE.
Storage
Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Data Sheet MSDS
Datasheet MSDS
For research or industrial raw materials, not for personal medical use!

Online Inquiry
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    1-516-512-3133
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