Recombinant Human ACE2 Protein (18-116), N-GST-tagged
Product Description
Cat
IMP-8815
Official Symbol
ACE2
Product Overview
Human ACE2 partial ORF (NP_068576.1, 18 a.a.-116 a.a.) recombinant protein with GST tag at N-terminal was expressed in wheat germ expression system (in vitro).
Description
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Expression System
Wheat Germ (in vitro)
Species
Human
Tag
N-GST
Form
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
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