Recombinant Human ACVR1B Protein Full Length, N-GST and C-His-tagged

Product Description

Cat

IMP-7303

Official Symbol

ACVR1B

Product Overview

Purified recombinant protein of Human activin A receptor, type IB (ACVR1B), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli.

Description

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Expression System

E. coli

Species

Human

Tag

N-GST and C-His

Form

25mM Tris, pH 8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl

Molecular Mass

84.8 kDa

Protein length

Full Length

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining.

Storage

Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Concentration

> 50 μg/mL as determined by microplate BCA method.

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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