Recombinant Human ACVRL1 Protein (139-503), N-GST-tagged
Product Description
Cat
IMP-9220
Official Symbol
ACVRL1
Product Overview
Human ACVRL1 (NP_000011.2, 139 a.a.-503 a.a.) partial recombinant protein with GST-tag at N-terminal using baculovirus expression system.
Description
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Expression System
Viruses
Species
Human
Tag
N-GST
Form
Liquid, 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Protein length
139-503
Purity
0.65
Applications
Functional Study
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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