Recombinant Human ADK Protein (22-362), His-tagged
Product Description
Cat
IMP-7983
Official Symbol
ADK
Product Overview
Human Adenosine Kinase/ADK protein (NP_006712, 22 a.a.-362 a.a.) partial recombinant protein with His tag was expressed in E. coli.
Description
This gene encodes adenosine kinase, an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
Expression System
E. coli
Species
Human
Tag
His
Form
Liquid, In 20 mM Tris-HCl, 50 mM NaCl, pH 8.0 (20% glycerol, 1 mM DTT, 1 mM EDTA)
Molecular Mass
40.5 kDa
Protein length
22-362
Purity
> 95% by SDS-PAGE
Applications
SDS-PAGE
Storage
Store at -20 centigrade. For long term storage store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

15% SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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