Recombinant Human AREG Protein (1-252), N-GST-tagged

Product Description

Cat

IMP-8524

Official Symbol

AREG

Product Overview

Human AREG full-length ORF ( NP_001648.1, 1 a.a.-252 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ (in vitro).

Description

The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.

Expression System

Wheat Germ (in vitro)

Species

Human

Tag

N-GST

Form

50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Molecular Mass

54.3 kDa

Protein length

1-252

AA Sequence

MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKKLRQENGNVHAIA

Applications

ELISA; WB (Recombinant protein); Antibody Production; Protein Array

Notes

Best use within three months from the date of receipt of this protein.

Storage

Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

SDS-PAGE

12.5% SDS-PAGE Stained with Coomassie Blue.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry