Description
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
Storage
Stored at -20 to -80 centigrade for 12 month. After reconstitution with sterile water at 0.1 mg/mL, store at -20 to -80 centigrade for 3 months, store at 4 centigrade for 1 month. Aliquot to avoid repeated freezing and thawing.
