Recombinant Human BMPR1A Protein (187-532), GST-tagged
Product Description
Cat
IMP-8872
Official Symbol
BMPR1A
Product Overview
Human BMPR1A (NP_004320.2, 187 a.a.-532 a.a.) Q223D mutant partial recombinant protein with GST tag was expressed in baculovirus infected Sf21 cells.
Description
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Expression System
Insect cells
Species
Human
Tag
GST
Form
Liquid, In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
Molecular Mass
66 kDa
Protein length
187-532
Purity
60 % by SDS-PAGE/CBB staining
Applications
Functional Study; SDS-PAGE
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

Loading 1 μg protein in SDS-PAGE

Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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