Recombinant Human BTK Protein (1-659), N-GST-tagged

Product Description

Cat

IMP-8905

Official Symbol

BTK

Product Overview

Human BTK full-length ORF ( NP_000052.1, 1 a.a.-659 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ (in vitro).

Description

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Expression System

Wheat Germ (in vitro)

Species

Human

Tag

N-GST

Form

50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Molecular Mass

98.12 kDa

Protein length

1-659

AA Sequence

MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSSHRKTKKPLPPTPEEDQILKKPLPPEPAAAPVSTSELKKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES

Applications

ELISA; WB (Recombinant protein); Antibody Production; Protein Array

Notes

Best use within three months from the date of receipt of this protein.

Storage

Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

SDS-PAGE

12.5% SDS-PAGE Stained with Coomassie Blue.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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