Description
This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Bio-activity
Measured by its binding ability in a functional ELISA. When Recombinant Human CD277/BTN3A1 Fc Chimera Protein is immobilized at 10.0 μg/mL, 100 μL/well, the concentration of Biotinylated Recombinant Human BTN2A1 Fc Chimera Avi-tag that produces 50% of the binding response is 1.00-6.00 μg/mL.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after opening.
3 months, -20 to -70 centigrade under sterile conditions after opening.
