Recombinant Human CD244 Protein (1-365), N-GST-tagged

Product Description

Cat

IMP-8741

Official Symbol

CD244

Product Overview

Human CD244 full-length ORF ( NP_057466.1, 1 a.a.-365 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ (in vitro).

Description

Natural killer (NK) cells express both activating and inhibitory cell surface receptors. Inhibitory signaling receptors all possess cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, or ITIMs, whereas the activating receptors lack ITIMs and associate with DAP12, which contains an immunoreceptor tyrosine-based activation motif, or ITAM. Killer cell immunoglobulin (Ig)-like receptors, or KIRs, and other NK cell receptors interact with major histocompatibility complex (MHC) molecules. Members of the CD2 family adhere to each other instead. The cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function.

Expression System

Wheat Germ (in vitro)

Species

Human

Tag

N-GST

Form

50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Molecular Mass

67.5 kDa

Protein length

1-365

AA Sequence

MLGQVVTLILLLLLKVYQGKGCQGSADHVVSISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNLSLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVALSCLVSRDGNVSYAWYRGSKLIQTAGNLTYLDEEVDINGTHTYTCNVSNPVSWESHTLNLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEFLTIYEDVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTSQEPAYTLYSLIQPSRKSGSRKRNHSPSFNSTIYEVIGKSQPKAQNPARLSRKELENFDVYS

Applications

ELISA; WB (Recombinant protein); Antibody Production; Protein Array

Notes

Best use within three months from the date of receipt of this protein.

Storage

Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

SDS-PAGE

12.5% SDS-PAGE Stained with Coomassie Blue.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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