Recombinant Human CD244 Protein (Cys22-Arg221), C-hFc-tagged

Product Description

Cat

IMP-10279

Official Symbol

CD244

Product Overview

Recombinant human 2B4/CD244/SLAMF4 protein (Cys22-Arg221) with a Human IgG1 (Glu98-Lys330) Fc tag at C-terminus was expressed in Mouse myeloma cell line.

Description

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Expression System

Mouse myeloma cell line

Species

Human

Tag

C-hFc

Predicted N Terminal

Cys22

Form

Lyophilized from a 0.2 μm filtered solution in PBS.

Molecular Mass

Predicted Molecular Mass: 48.8 kDa (monomer)
SDS-PAGE: 81 kDa, reducing conditions

Protein length

Cys22-Arg221

Bio-activity

Measured by its binding ability in a functional ELISA. Immobilized rh2B4/Fc Chimera at 5 μg/mL (100 μL/well) can bind rhCD48 with a linear range of 0.06-4 μg/mL.

Endotoxin

<0.01 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Notes

Disulfide-linked homodimer

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 100 μg/mL in sterile PBS.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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