Recombinant Human CD244 Protein (Cys22-Arg221), C-hFc-tagged

Product Description

Cat

IMP-10279

Official Symbol

CD244

Product Overview

Recombinant human 2B4/CD244/SLAMF4 protein (Cys22-Arg221) with a Human IgG1 (Glu98-Lys330) Fc tag at C-terminus was expressed in Mouse myeloma cell line.

Description

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Expression System

Mouse myeloma cell line

Species

Human

Tag

C-hFc

Predicted N Terminal

Cys22

Form

Lyophilized from a 0.2 μm filtered solution in PBS.

Molecular Mass

Predicted Molecular Mass: 48.8 kDa (monomer)
SDS-PAGE: 81 kDa, reducing conditions

Protein length

Cys22-Arg221

Bio-activity

Measured by its binding ability in a functional ELISA. Immobilized rh2B4/Fc Chimera at 5 μg/mL (100 μL/well) can bind rhCD48 with a linear range of 0.06-4 μg/mL.

Endotoxin

<0.01 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Notes

Disulfide-linked homodimer

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 100 μg/mL in sterile PBS.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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