Description
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Bio-activity
Measured by its binding ability in a functional ELISA. When Recombinant Human CD48/SLAMF2 Fc Chimera Protein is immobilized at 1.0 μg/mL, 100 μL/well, the concentration of Biotinylated Recombinant Human 2B4/CD244/SLAMF4 Fc Chimera Avi-tag that produces 50% of the optimal binding response is 35.0-350 ng/mL.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
