Recombinant Human CD27 Protein (20-191), hIgG/His-tagged
Product Description
Cat
IMP-9217
Official Symbol
CD27
Product Overview
Human CD27 (P26842, 20 a.a.-191 a.a.) partial recombinant protein with hIgG-His tag expressed in HEK293 cells.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Expression System
HEK293
Species
Human
Tag
hIgG/His
Form
Liquid, In PBS, pH 7.4 ( 10% glycerol)
Molecular Mass
46.2 kDa
Protein length
20-191
AA Sequence
ATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIRLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
Endotoxin
< 1 EU/μg of protein by the LAL method.
Purity
> 95% by SDS-PAGE
Applications
Functional Study; SDS-PAGE
Storage
Store at 4 centigrade for 1 week. For long term storage store at -20 to -80 centigrade. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

SDS-PAGE Stained with Coomassie Blue. SDS-PAGE analysis of CD27 (Human) Recombinant Protein.

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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