Recombinant Human CD276 Protein (Leu29-Pro245), C-mFc and 6×His-tagged
Product Description
Cat
IMP-7426
Official Symbol
CD276
Product Overview
Recombinant Human B7-H3 Protein with C-Mouse Fc (Pro99-Lys330) and 6×His tag was expressed in HEK293.
Description
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Expression System
HEK293
Species
Human
Tag
C-mFc and 6×His
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5-8 % trehalose is added as protectants before lyophilization.
Molecular Mass
70-75 kDa
Protein length
Leu29-Pro245
Purity
> 95%
Applications
ELISA
Storage
Store the lyophilized protein at -20 centigrade. After reconstitution, store the protein at -80 centigrade for 12 months. Avoid repeated freezing and thawing.
Stability: 12 months from date of despatch.
Reconstitution
Reconstitute with deionized water.
SDS-PAGE
SDS-PAGE

Bioactivity-ELISA 1
Bioactivity

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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