Recombinant Human CD38 Protein (Val43-Ile300), C-hFc and 6×His-tagged
Product Description
Cat
IMP-7435
Official Symbol
CD38
Product Overview
Recombinant Human CD38 Protein with C-Human Fc (Glu99-Ala330) and 6×His was expressed in HEK293.
Description
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Expression System
HEK293
Species
Human
Tag
C-hFc and 6×His
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5-8 % trehalose is added as protectants before lyophilization.
Molecular Mass
70-72 kDa
Protein length
Val43-Ile300
Purity
> 95%
Applications
ELISA
Storage
Store the lyophilized protein at -20 centigrade. After reconstitution, store the protein at -80 centigrade for 12 months. Avoid repeated freezing and thawing.
Stability: 12 months from date of despatch.
Reconstitution
Reconstitute with deionized water.
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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