Recombinant Human CD47 Protein [ (Gln19-Gln141) + (Val198-Ala207) + (Ser257-Gly268) ], C-mFc and 6×His-tagged
Product Description
Cat
IMP-7449
Official Symbol
CD47
Product Overview
Recombinant Human CD47 Protein with C-Mouse Fc (Pro99-Lys330) and 6×His tag was expressed in HEK293.
Description
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
Expression System
HEK293
Species
Human
Tag
C-mFc and 6×His
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5-8 % trehalose is added as protectants before lyophilization.
Molecular Mass
60 kDa
Protein length
CD47 (Gln19-Gln141) +CD47 (Val198-Ala207) +CD47 (Ser257-Gly268)
Purity
> 95%
Applications
ELISA
Storage
Store the lyophilized protein at -20 centigrade. After reconstitution, store the protein at -80 centigrade for 12 months. Avoid repeated freezing and thawing.
Stability: 12 months from date of despatch.
Reconstitution
Reconstitute with deionized water.
SDS-PAGE
SDS-PAGE

Bioactivity-ELISA 1
Bioactivity

Bioactivity-ELISA 2
Bioactivity

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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