Recombinant Human CD52 Protein (25-36aa), C-hIgG-His-Tagged
Product Description
Cat
IMP-9485
Official Symbol
CD52
Product Overview
Recombinant human CD52, fused to hIgGHis-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description
CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytesderived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression.
Expression System
Baculovirus
Species
Human
Tag
C-hIgG-His
Form
Liquid in Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Molecular Mass
28.2 kDa (251 aa)
Protein length
25-36
AA Sequence
GQNDTSQTSSPSLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
Endotoxin
< 1 EU/μg of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Applications
SDS-PAGE
Notes
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage
Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration
0.5 mg/mL (determined by absorbance at 280nm)
SDS-PAGE
SDS-PAGE

3 μg by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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