Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Storage
Stored at -20 to -80 centigrade. After reconstitution with sterile water not less than 0.1 mg/mL, store at -20 to -80 centigrade for 12 months, store at 4 centigrade for 1 month. Aliquot to avoid repeated freezing and thawing.