Recombinant Human CD8A Protein (22-182aa), C-His-Tagged
Product Description
Cat
IMP-9506
Official Symbol
CD8A
Product Overview
Recombinant human CD8 alpha, fused to His-tag at Cterminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description
CD8 alpha, also known as T-cell surface glycoprotein CD8 alpha chain isoform 1, is a member of integralmembrane glycoprotein that plays an essential role in the immune response and serves multiple functions inresponses. It interacts with the T-cell receptor and the MHC class I proteins presented by antigen presentingcells. Homodimers of this protein at the cell surface provides a survival mechanism allowing conjugation and lysisof multiple target cells in NK-cells.
Expression System
Baculovirus
Species
Human
Tag
C-His
Form
Liquid in Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Molecular Mass
18.7 kDa (170 aa)
Protein length
22-182
AA Sequence
<ADP>SQFRVSPLDRTWNLGETVELKCQVLLSNPTSGCSWLFQPRGAAASPTFLLYLSQNKPKAAEGLDTQRFSGKRLGDTFVLTLSDFRRENEGYYFCSALSNSIMYFSHFVPVFLPAKPTTTPAPRPPTPAPTIASQPLSLRPEACRPAAGGAVHTRGLDFACD<HHHHHH>
Endotoxin
< 1 EU/μg of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Applications
SDS-PAGE
Notes
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage
Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration
0.5 mg/mL (determined by absorbance at 280nm)
SDS-PAGE
SDS-PAGE

3 μg by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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