Recombinant Human CEACAM1 Protein (35-428), 6×His-tagged
Product Description
Cat
IMP-8842
Official Symbol
CEACAM1
Product Overview
Human CEACAM1 (NP_001703.2, 35 a.a.-428 a.a.) partial recombinant protein with a 6×His tag at the C-terminus expressed in HEK293 cells.
Description
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined.
Expression System
HEK293
Species
Human
Tag
6×His
Form
Lyophilized from a 0.22 μM filtered solution of PBS, pH 7.4.
Protein length
35-428
Purity
> 97% by SDS-PAGE
Applications
Immunogen; SDS-PAGE
Storage
Store at -80 centigrade on dry atmosphere, lyophilized antibodies are stable at least 2 years. After reconstitution with deionized water, store at -20 centigrade or lower. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

SDS-PAGE Stained with Coomassie Blue

Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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