Recombinant Human CEACAM5 Protein (Lys35-Ala685), C-6×His-tagged

Product Description

Cat

IMP-10241

Official Symbol

CEACAM5

Product Overview

Recombinant human CEACAM-5/CD66e protein (Lys35-Ala685) with a C-terminal 6×His tag was expressed in Mouse myeloma cell line.

Description

This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.

Expression System

Mouse myeloma cell line

Species

Human

Tag

C-6×His

Predicted N Terminal

Lys35

Form

Lyophilized from a 0.2 μm filtered solution in PBS.

Molecular Mass

Predicted Molecular Mass: 72 kDa
SDS-PAGE: 155-180 kDa, reducing conditions

Protein length

Lys35-Ala685

Bio-activity

Measured by its binding activity in a functional ELISA. Recombinant Human CEACAM-5/CD66e can bind Recombinant Human Galectin-4 with an estimated Kd <4 nM.

Endotoxin

<0.01 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 100 μg/mL in sterile PBS.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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