Recombinant Human CLEC4A Protein (Gln70-Leu237), N-10×His-tagged
Product Description
Cat
IMP-10212
Official Symbol
CLEC4A
Product Overview
Recombinant human DCIR/CLEC4A protein (Gln70-Leu237) with an N-terminal 10-His tag was expressed in Mouse myeloma cell line.
Description
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Expression System
Mouse myeloma cell line
Species
Human
Tag
N-10×His
Predicted N Terminal
His
Form
Lyophilized from a 0.2 μm filtered solution in PBS.
Molecular Mass
Predicted Molecular Mass: 21 kDa
SDS-PAGE: 23-38 kDa, reducing conditions
Protein length
Gln70-Leu237
Bio-activity
Measured by the ability of the immobilized protein to support the adhesion of SW480 human fibroblast carcinoma cells. The ED50 for this effect is 0.8-6.4 μg/mL.
Endotoxin
<0.10 EU/μg of the protein by the LAL method.
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 250 μg/mL in PBS.
Bioactivity-ELISA 1
Bioactivity

Measured by the ability of the immobilized protein to support the adhesion of SW480 human fibroblast carcinoma cells. The ED50 for this effect is 0.8-6.4 μg/mL.

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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