Recombinant Human CLEC4C Protein (Phe46-Ile213), N-hFc-tagged
Product Description
Cat
IMP-10214
Official Symbol
CLEC4C
Product Overview
Recombinant human DLEC/CLEC4C/BDCA-2 protein (Phe46-Ile213) with a Human IgG1 (Ser102-Lys330) Fc tag at N-terminus was expressed in Mouse myeloma cell line..
Description
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Expression System
Mouse myeloma cell line
Species
Human
Tag
N-hFc
Predicted N Terminal
Ser102 (Fc)
Form
Lyophilized from a 0.2 μm filtered solution in PBS.
Molecular Mass
Predicted Molecular Mass: 46 kDa
SDS-PAGE: 55-61 kDa, reducing conditions
Protein length
Phe46-Ile213
Bio-activity
Measured by its ability to bind fluorescein-conjugated S. aureus Bioparticles. Jiang, Y. et al. (2006) J. Biol. Chem. 281:11834. The ED50 for this effect is 0.5-2.5 μg/mL.
Endotoxin
<0.10 EU/μg of the protein by the LAL method.
Purity
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 250 μg/mL in PBS.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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