Recombinant Human CLEC4C Protein (Phe46-Ile213), N-hFc-tagged
Product Description
Cat
IMP-10214
Official Symbol
CLEC4C
Product Overview
Recombinant human DLEC/CLEC4C/BDCA-2 protein (Phe46-Ile213) with a Human IgG1 (Ser102-Lys330) Fc tag at N-terminus was expressed in Mouse myeloma cell line..
Description
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Expression System
Mouse myeloma cell line
Species
Human
Tag
N-hFc
Predicted N Terminal
Ser102 (Fc)
Form
Lyophilized from a 0.2 μm filtered solution in PBS.
Molecular Mass
Predicted Molecular Mass: 46 kDa
SDS-PAGE: 55-61 kDa, reducing conditions
Protein length
Phe46-Ile213
Bio-activity
Measured by its ability to bind fluorescein-conjugated S. aureus Bioparticles. Jiang, Y. et al. (2006) J. Biol. Chem. 281:11834. The ED50 for this effect is 0.5-2.5 μg/mL.
Endotoxin
<0.10 EU/μg of the protein by the LAL method.
Purity
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 250 μg/mL in PBS.
Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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