Recombinant Human CYP1B1 Protein (Leu40-Ala305), N-His-tagged
Product Description
Cat
IMP-7520
Official Symbol
CYP1B1
Product Overview
Purified recombinant protein of Human cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1), Leu40-Ala305, with N-terminal His tag, expressed in E. coli.
Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
Expression System
E. coli
Species
Human
Tag
N-His
Form
50mM Tris, 8M Urea, pH 8.0
Molecular Mass
30 kDa
Protein length
Leu40-Ala305
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining.
Storage
Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
> 50 μg/mL as determined by microplate BCA method.
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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