Product Overview
Recombinant human Dkk-1 protein, fused to His-tag at C-terminus, was expressed in insect cell using baculovirus expression system and purified by using conventional chromatography.
Description
Dickkopf-related protein 1, also known as Dkk-1, is a member of the Dkk protein family including Dkk-1, 2, 3 and - 4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Form
Liquid in Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol, 2mM DTT, 2mM EDTA, 0.1mM PMSF
