Recombinant Human DKK3 Protein, Tag Free
Product Description
Cat
IMP-7032
Official Symbol
DKK3
Product Overview
Recombinant human DKK-3 protein without tag was produced in CHO.
Description
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).[UniProtKB/Swiss-Prot Function]
Expression System
CHO
Species
Human
Tag
Tag free
Form
Presentation State: Purified
State: Lyophilized purified protein
Stabilizer: None
Molecular Mass
39-49 kDa
AA Sequence
APAPTATSAPVKPGPALSYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSLTEEMALREPAAAAAALLGGEEI
Purity
> 98% by SDS-PAGE and HPLC analyses.
Notes
Centrifuge vials before opening!
Storage
Store lyophilized at 2-8 centigrade for 6 months or at -20 centigrade long term. After reconstitution store the antibody undiluted at 2-8 centigrade for one month or (in aliquots) at -20 centigrade long term. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Reconstitution
We recommended a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other aqueous buffers and stored at 4 centigrade for one week or at -20 centigrade for future use.
Data Sheet MSDS
Datasheet MSDS
For research or industrial raw materials, not for personal medical use!

Online Inquiry
Contact Info
Phone
  • 1-631-559-9269
    1-516-512-3133
Fax
  • 1-631-938-8127
Email
Address
Copyright © 2025 Creative BioMart. All rights reserved.

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy

Accept Cookies
x