Recombinant Human ENG Protein, Tag Free
Product Description
Cat
IMP-6685
Official Symbol
ENG
Product Overview
Recombinant human CD105/Endoglin protein without tag was expressed in insect cells.
Description
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Expression System
Insect cells
Species
Human
Tag
Tag free
Form
Presentation State: Purified
State: Lyophilized without buffer and stabilizer.
Molecular Mass
90 kDa
Endotoxin
< 0.1 ng/μg
Purity
> 95% by SDS-PAGE and visualised by silver stain.
Notes
Centrifuge vials before opening!
Storage
Store lyophilized sCD105 at -20 centigrade. Reconstituted should be stored in working aliquots at -20 to -70 centigrade. For long term storage as a dilute solution, a carrier protein (e.g. 0.1% HSA or BSA) should be added to the vial. Avoid repeated freeze-thaw cycles!
Shelf life: One year from despatch.
Reconstitution
The carrier-free protein should be used immediately upon reconstitution to avoid losses in activity due to non-specific binding to the inside surface of the vial. For long term storage as a dilute solution, a carrier protein (e.g. 0.1% HSA or BSA) should be added to the vial.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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