Recombinant Human EPCAM Protein (24-265), N-His/Flag/StrepII-tagged

Product Description

Cat

IMP-8617

Official Symbol

EPCAM

Product Overview

Purified EPCAM (NP_002345.1, 24-265) human recombinant protein with His-Flag-StrepII tag at N-terminus was expressed in human HEK293H cells.

Description

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

Expression System

HEK293H

Species

Human

Tag

N-His/Flag/StrepII

Form

Liquid, In PBS.

Molecular Mass

52.69 kDa

Protein length

24-265

AA Sequence

QEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVICSKLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSTCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEITTRYQLDPKFITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNGEQLDLDPGQTLIYYVDEKAPEFSMQGLK

Applications

WB; ELISA; SDS-PAGE; Protein Interaction

Storage

Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Concentration

≥ 10 μg/mL

SDS-PAGE

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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