Recombinant Human FASLG Protein, His-tagged
Product Description
Cat
IMP-6759
Official Symbol
FASLG
Product Overview
Recombinant human CD178/Fas Ligand protein with His tag was expressed in CHO.
Description
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
Expression System
CHO
Species
Human
Tag
His
Form
Presentation State: Purified
State: Lyophilized purified protein from 10mM Sodium Phosphate, pH 7.5 + 150mM NaCl
Stabilizer: None
Molecular Mass
17.9 kDa
AA Sequence
HHHHHHHHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL
Endotoxin
< 0.1 ng/μg
Purity
> 95% by SDS-PAGE and HPLC analysis.
Storage
Store lyophilized at 2-8 centigrade for 6 months or at -20 centigrade long term. After reconstitution store the antibody undiluted at 2-8 centigrade for one month or (in aliquots) at -20 centigrade long term. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Reconstitution
Restore in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other aqueous buffers and stored at 4 centigrade for one week or at -20 centigrade for future use.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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