Recombinant Human FCER2 Protein (Asp48-Ser321), N-9×His-tagged

Product Description

Cat

IMP-9663

Official Symbol

FCER2

Product Overview

Recombinant human CD23/Fc epsilon RII protein (Asp48-Ser321) with an N-terminal 9-His tag was expressed in Mouse myeloma cell line.

Description

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Expression System

Mouse myeloma cell line

Species

Human

Tag

N-9×His

Predicted N Terminal

His

Form

Lyophilized from a 0.2 μm filtered solution in PBS.

Molecular Mass

Predicted Molecular Mass: 32 kDa
SDS-PAGE: 41 kDa, reducing conditions

Protein length

Asp48-Ser321

Bio-activity

Measured by its binding ability in a functional ELISA. Immobilized rhCD23 at 2 μg/mL (100 μL/well) can bind human IgE with a linear range of 0.015-1 μg/mL.

Endotoxin

<0.10 EU/μg of the protein by the LAL method.

Purity

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 100 μg/mL in sterile PBS.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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