Recombinant Human FCGR2A Protein, C-His-tagged

Product Description

Cat

IMP-1994

Official Symbol

FCGR2A

Product Overview

Recombinant extracellular domain (Met1-Ile218) of human FCGR2A (P12318-1, with Natural variant His 167 Arg) was expressed with a C-terminal polyhistidine tag.

Description

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

Expression System

HEK293

Species

Human

Tag

C-His

Predicted N Terminal

Gln 34

Form

Lyophilized from sterile PBS, pH 7.5, 5 % trehalose, 5% mannitol and 0.01% Tween80.

Molecular Mass

The recombinant human FCGR2A consists of 196 amino acids after removal of the signal peptide and predicts a molecular mass of 22 kDa. It migrates as an approximately 30 kDa protein due to glycosylation by SDS-PAGE under reducing conditions.

Protein length

Met1-Ile218

Endotoxin

< 1.0 EU/μg of the protein as determined by the LAL method

Purity

> 97 % as determined by SDS-PAGE

Storage

Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SDS-PAGE

Bioactivity-BLI 1

Loaded Anti-CD32A Antibody, Mouse Monoclonal on AMC Biosensor, can bind CD32A Protein, Human, Recombinant (167 Arg, His Tag) with an affinity constant of 6.8 nM as determined by Octet RED System.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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