Product Overview
Purified recombinant protein of Human Fc fragment of IgG, low affinity IIIb, receptor (CD16b) (FCGR3B) with a C-Fc&His tag was expressed in HEK293.
Description
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
