Product Overview
Recombinant Human FGL1 Protein(NP_004458.3)(Leu23-Ile312) is expressed in HEK293, fused with a Avi, 6His tag at the C-terminus.
Description
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.
Form
Supplied as a 0.2 μm filtered solution of 20mM Tris, 300mM Nacl, 10%Glycerol, 2mM EDTA, pH8.0.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
