Recombinant Human FGR Protein (1-529), GST/His-tagged
Product Description
Cat
IMP-8186
Official Symbol
FGR
Product Overview
Human FGR (NM_005248.1, 1 a.a.-529 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.
Description
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Expression System
Insect cells
Species
Human
Tag
GST/His
Form
Liquid, In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Molecular Mass
93.934 kDa
Protein length
1-529
Applications
Functional Study; SDS-PAGE
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration
0.055 μg/μL
SDS-PAGE
Quality Control Testing

2 μg/lane SDS-PAGE Stained with Coomassie Blue

Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

Online Inquiry
Contact Info
Phone
  • 1-631-559-9269
    1-516-512-3133
Fax
  • 1-631-938-8127
Address

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