Recombinant Human FGR Protein (1-529), N-GST-tagged
Product Description
Cat
IMP-8187
Official Symbol
FGR
Product Overview
Human FGR (NP_005239.1, 1 a.a.-529 a.a.) full length recombinant protein with GST-tag at N-terminal using baculovirus expression system.
Description
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Expression System
Viruses
Species
Human
Tag
N-GST
Form
Liquid, 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Protein length
1-529
Purity
0.59
Applications
Functional Study
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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