Recombinant Human FOLR2 Protein (Ser20-Arg2212), N-His-tagged
Product Description
Cat
IMP-7582
Official Symbol
FOLR2
Product Overview
Purified recombinant protein of Human folate receptor 2 (fetal) (FOLR2), transcript variant 1, Ser20-Arg221, with N-terminal His tag, expressed in E.coli.
Description
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Expression System
E. coli
Species
Human
Tag
N-His
Form
50mM Tris, 8M Urea, pH 8.0
Molecular Mass
23.5 kDa
Protein length
Ser20-Arg2212
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining.
Storage
Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
> 50 μg/mL as determined by microplate BCA method.
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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