Recombinant Human GGCT Protein, N-His-tagged
Product Description
Cat
IMP-4533
Official Symbol
GGCT
Product Overview
Recombinant mature form of human GGCT (O75223-1) (Met1-Leu188) was expressed with a polyhistide tag at the N-terminus.
Description
GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Pseudogenes of GGCT gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Expression System
E. coli
Species
Human
Tag
N-His
Predicted N Terminal
His
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.
Molecular Mass
The recombinant human GGCT consists of 203 amino acids and predicts a molecular mass of 22.8 KDa. It migrates as an approximately 23-26 KDa band in SDS-PAGE under reducing conditions.
Protein length
Met1-Leu188
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by SDS-PAGE
Storage
Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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