Recombinant Human HAVCR2 Protein (Glu23-Arg200), C-Fc-tagged
Product Description
Cat
IMP-7609
Official Symbol
HAVCR2
Product Overview
Purified recombinant protein of human T-cell immunoglobulin mucin receptor 3 (TIM3), with C-terminal Fc tag, expressed in human cells.
Description
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Expression System
HEK293
Species
Human
Tag
C-Fc
Form
PBS, pH7.4, 10% glycerol
Molecular Mass
45 kDa
Protein length
Glu23-Arg200
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining.
Storage
Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
> 50 μg/mL as determined by microplate BCA method.
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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