Recombinant Human IL13 Protein, Tag free
Product Description
Cat
IMP-8479
Official Symbol
IL13
Product Overview
Human IL13 (P35225, 33 a.a.-146 a.a.) partial recombinant protein expressed in CHO cells.
Description
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Expression System
CHO
Species
Human
Tag
Tag free
Form
Lyophilized from PBS. Reconstitute the lyophilized powder in ddH2O up to 100 μg/mL.
Molecular Mass
25-45 kDa
Protein length
33-146
AA Sequence
SPGPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGRFN
Endotoxin
< 0.2 EU/μg of protein (gel clotting method)
Purity
> 95% by SDS-PAGE
Applications
Functional Study; SDS-PAGE
Storage
Store at 4 centigrade for 1 week. For long term storage store at -20 to -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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