Product Overview
Recombinant human IL17F protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description
IL17F, also known as Interleukin-17F, is a cytokine that shares sequence similarity with IL17. It is expressed in activated CD4+ T-cells and activated monocytes. The biological activities mediated by IL17F are similar to those of IL-17. This protein stimulates production of IL-6, IL-8, G-CSF, and regulates cartilage matrix turnover by increasing matrix release and inhibiting new matrix synthesis. It also inhibits angiogenesis and induces production of IL-2, TGF-beta, and monocyte chemoattractant protein-1 in endothelial cells.
