Recombinant Human IL17F Protein, Tag free

Product Description

Cat

IMP-7951

Official Symbol

IL17F

Product Overview

Human IL17F (Q96PD4) recombinant protein expressed in E. coli.

Description

The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.

Expression System

E. coli

Species

Human

Tag

Tag free

Form

Lyophilized from 10 mM sodium citrate, pH 3.0

Molecular Mass

30 kDa

AA Sequence

MRKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ

Endotoxin

< 0.1 EU/μg

Applications

Functional Study; SDS-PAGE

Storage

Store at -20 centigrade on dry atmosphere. After reconstitution with sterilized water, store at -20 centigrade or lower. Aliquot to avoid repeated freezing and thawing.

SDS-PAGE

1 μg/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue. Non-reducing conditions

Bioactivity-ELISA 1

Serial dilutions of human IL17F (starting at 400 ng/mL) were added to NIH/3T3 cells. After 48 hours, production of mouse IL6 was measured and the linear portion of the curve was us used to calculate the ED50.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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