Description
This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
Bio-activity
Measured by its binding ability in a functional ELISA. When Recombinant Human IL-1 RII Fc Chimera is immobilized at 0.5 μg/mL (100 μL/well), in the presence of Recombinant Human IL-1 beta/IL-1F2, it binds to Biotinylated Recombinant Human IL-1 RAcP/IL-1 R3 Fc Chimera Avi-tag with an ED50 of 4.00-36.0 ng/mL.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
