Recombinant Human IL1RL2 Protein (Asp20-Tyr337), C-hFc-tagged
Product Description
Cat
IMP-10495
Official Symbol
IL1RL2
Product Overview
Recombinant human IL-1Rrp2/IL-1R6 protein (Asp20-Tyr337) with a Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Sf 21 cells.
Description
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Expression System
Sf 21 cells
Species
Human
Tag
C-hFc
Predicted N Terminal
Asp20
Form
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Molecular Mass
Predicted Molecular Mass: 62.8 kDa (monomer)
SDS-PAGE: 80 kDa, reducing conditions
Protein length
Asp20-Tyr337
Bio-activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant human (rh) IL-1F5, rhIL-1F8, rhIL-1F6 or rhIL-1F9 at 1 μg/mL (100 μL/well) can bind rhIL-1Rrp2 Fc Chimera with a linear range of 0.15-5 μg/mL.
Endotoxin
<0.10 EU/μg of the protein by the LAL method.
Purity
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Notes
Disulfide-linked homodimer
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 100 μg/mL in sterile PBS.
Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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