Product Overview
Purified recombinant protein of Human interleukin 23 receptor (IL23R), Lys57-Gly355, with N-terminal His tag, expressed in E.coli.
Description
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.