Recombinant Human IL25 Protein, Tag free

Product Description

Cat

IMP-8867

Official Symbol

IL25

Product Overview

Human IL25 (Q9H293) recombinant protein expressed in E. coli.

Description

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. This cytokine can induce NF-kappaB activation, and stimulate the production of IL8. Both this cytokine and IL17B are ligands for the cytokine receptor IL17BR. Studies of the similar gene in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Expression System

E. coli

Species

Human

Tag

Tag free

Form

Lyophilized, No additive

Molecular Mass

35.5 kDa

AA Sequence

MYSHWPSCCPSKGQDTSEELLRWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG

Endotoxin

< 0.1 EU/μg

Applications

Functional Study; SDS-PAGE

Storage

Store at -20 centigrade on dry atmosphere. After reconstitution with sterilized 10 mM HCl, store at -20 centigrade or lower. Aliquot to avoid repeated freezing and thawing.

Bioactivity-ELISA 1

Human PBMCs were cultured with 0 to 1000 ng/mL human IL25. Human IL-8 production was measured after 48 hours and the linear portion of the curve was us used to calculate the ED50.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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