Description
The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene.
Bio-activity
Measured by its binding ability in a functional ELISA. When Recombinant Human ST2/IL-33R Fc Chimera is immobilized at 0.5 μg/mL (100 μL/well), Biotinylated Recombinant Human IL-33 binds with an ED50 of 0.900-9.00 ng/mL.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
